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       COSMETIC

       Hair Restoration
 

 
What is hair?
Hair is a characteristic skin appendage found only in mammals whose function was basically meant to provide insulation, but with evolution it has lost most of its protective function and instead plays an important role in social interactions.

How many hairs does a human head have?
A human head has anywhere between 100,000 and 150,000 hairs. Oriental heads have most hairs and redheads have the least. Apart from the palms and soles almost all skin has follicles. But not all hair grows to the same length or at the same rate.

What is a hair follicle?

Hair follicle is stocking like in growth of the skin epithelium which manufactures and anchors the hair to the skin

How does a hair follicle develop?
In humans, follicle formation begins on the head in the fourth fetal month of gestation, and then moves downward to the remainder of the body. Follicles first produce soft, short and fine hairs, which are called “lanugo” hairs.

What are the different parts of the hair follicle?
The follicles are slanted in epidermis and an oblique muscle the arrector pili runs from the middle of the follicle wall to the dermo epidermal junction, additionally one or more sebaceous glands open into the follicle.The follicle may be divided into vertical components : Infundibulum, Isthumus, Suprabulbar region and Bulb

What is the composition of hair?
The hair as we see it is a compact structure made up of dead cells. Individual hairs are composed chiefly of the horny scleroprotein known as keratin and contain neither blood vessels nor nerves. They usually contain pigment (except in the case of albinos). The shaft of the hair consists of modified epithelial cells arranged in columns (cortex) surrounding a central medulla (or core) and covered with thin, flat scales (cuticle).

What is the density of hair on scalp?

Accurate quantitative analysis of scalp hair density is difficult and time consuming.
Scalp possesses the greatest density of hair fibers 300 – 500/cm2(different figures are quoted by different specialists ranging from 130-280/sqcm2), Chest about 100/cm2, Thigh about 50/cm2.

How does hair grow?
The hair follicle bulb is like a minute factory which manufactures cells continuously. As new cells are formed the older ones are pushed into the follicle towards the surface. The cells on reaching a particular point undergo cell death and are converted into a scleroprotein called keratin, which is then compacted to form the hair. This continuous activity is responsible for the hair growth.
During anagen the follicle actively grows hair.
During catagen the follicle is almost entirely degraded.
During telogen the follicle rests prior to re-initiation of an anagen phase and the growth of a new hair shaft. On any given day, human beings lose about 50-100 scalp hairs due to exogen, these are the hairs we find in our comb, brush and shower drain.  Shedding in excess of this may be due to an increase in the follicles of scalp hair in the telogen stage and should be addressed to contain hair loss.
At any given time approximately 90%of our scalp hair are in the growing phase and about 10% in the resting phase, if the scalp is healthy and not affected by any condition that causes hair loss.
Recently a fourth phase has been added based on the findings in patients of pattern hair loss. This is known as the Kenogen or the lag phase. This is the period after the hair has been shed and before the new hair formation begins. It is this phase that is prolonged in patients of Pattern Hair Loss
The normal growth rate of scalp hair is 0.3- 0.4 mm per day or roughly 1cm per month. Hair growth has a cyclical pattern that can be affected by a number of genetic, disease, medication or other factors to cause hair loss.

Long HairWhy do some people have very long hair? How long can your scalp hair grow?
If you do not cut your hair then you can grow it quite long, but there is an upper limit to the maximum length that you can grow your scalp hair.

There are various papers that examine the time duration for scalp hair follicles are actively producing a hair fiber. The most frequently quoted time period is 1000 days(2-6 YEARS), but this figure is a rough approximation. The time duration of anagen growth, plus knowing what length of hair fiber a scalp hair follicle can produce per day, will enable a calculation of the average maximum length that scalp hair can grow to. Research on humans suggests that active hair fiber growth production from scalp hair follicles may last from 500 to 1800 days. The scalp hair fiber growth rate is between 0.3 to 0.4mm a day. For the most part, the studies were done with male volunteers, but a few other studies indicate similar results for women too.
If you put it all together in a calculation, the research would suggest that the maximum length scalp hair can grow to, is between 20 and 60 centimeters. However, from the picture below you can see that some people are able to grow their hair much longer. The upper limit to scalp hair length is determined by our genes. Some people have genes for short hair, others grow hair much longer.

How is hair growth regulated?

The hormones called androgens are important control factors in hair growth and in inherited male and female patterns of hair loss. The androgen hormone testosterone and its metabolite dihydrotestosterone (DHT) are the key control factors:


Testosterone is a key control factor in the growth of beard, underarm and pubic hair.

Scalp hair loss is associated with presence of DHT in male and female pattern hair loss. DHT plus the presence and activity of hair loss gene(s) are the key factors underlying male and female pattern hair loss.

The androgens mediate their effect by binding to the androgen receptors present in the follicle. The testosterone is converted to DHT by the action of the enzyme 5-Alpha reductase.  The DHT then binds to the receptor and initiates its action