Evaluation of Efficacy of Intradermal Injection Therapy vs Derma Roller Application for Administration of QR678 Neo Hair Regrowth Formulation for the Treatment of Androgenetic Alopecia A Prospective S

Abstract

Background: Non-surgical hair restoration is one of the most exciting and innovative
fields in cosmetic surgery today. The addition of latest technique like derma roller
seeks to achieve better results for delivering pharmaceutical solution for hair growth
in comparison with topical administration.

Aim: We aim to compare intradermal injection vs. derma roller technique for admin-
istration of QR678Neo®hair regrowth therapy for the treatment of androgenetic alo-
pecia (AGA) in male and female patients.

Method: A sum of 50 patients in the age range of 20–70 years with AGA were in-
cluded and divided into 2 groups; Group A (intradermal) and Group B (derma roller).
Intradermal injection of QR678Neo® formulation and derma roller with superficial
application of QR678Neo® was given in each group. Assessment was done using hair
pull test, global photographic assessment, video-microscopic assessment, and patient
subjective assessment at baseline, 6 months, and 1 year.

Results: Significant diminution in hair fall was seen in both the groups. All the video-
microscopic assessment factors were better in intradermal injection group compared
to the derma roller group, but not significant. Erythema and pain were high in derma
roller group in compare to intradermal.

Conclusion: Derma roller technique is more convenient and easy to perform, espe-
cially when the availability of a trained person to carry out intradermal injection is
not feasible, it gives satisfactory results. It is also beneficial in needle phobic and ap-
prehensive patients. Though the results are more efficacious with intradermal scalp
injection technique, this study established satisfactory results with derma roller tech-
nique as well.

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